Postdoctoral Fellow
O pozici
Laboratory of Gnotobiology, Doly 183, 54922 Novy Hradek
We offer a stable environment in a top-notch laboratory and the opportunity to work with a unique gnotobiotic mouse model in the field of microbiome-host immunity crosstalk. Using a combination of cell cultures, organoids models, mouse models, and sequencing analyses the candidate will study the impact of selected bacteria or gut, nasal and lung microbiome on epithelial barrier function and immune responses. Candidate will determine the consequences of microbiota changes, focusing on the microbiome dysbiosis and disruption of epithelial barrier function in a mouse model of food and airway allergy or rhinitis. In addition, well-characterized probiotic strains and their postbiotics will be evaluated as a novel strategy to preserve epithelial barrier integrity, restore microbial balance, and ultimately reduce susceptibility to allergic diseases.
Required Skills and Qualifications:
PhD or equivalent scientific training in a relevant field, such as gnotobiology, microbiology, immunology, physiology, or a closely related discipline.
Experiences with RNA-Seq, flow cytometry, bioinformatic analyses or other immune-related analyses are an advantage.
Strong experimental or methodological expertise relevant to the research activities of the laboratory, with a demonstrated ability to design, conduct and analyze experimental results.
Strong interpersonal and communication skills, with the ability to work cooperatively within a multidisciplinary research environment.
Willingness to contribute to the broader activities of the laboratory, while developing and pursuing their own scientific interests.
What we offer:
6 weeks of vacation
Flexible working time
Contributions from the social fund (meal vouchers, Cafeterie, MultiSport, pension plan contribution, vaccination, children’s recreation, etc.)
Support for further education (language and professional courses, animal care certificates)
Subsidized accommodation in laboratory flat
Additional information
Starting date: January 2027
Applications must be submitted as a single PDF (in English) and include:
Curriculum Vitae (max 2 pages).
Cover letter (max 1 page): indicate your motivation to apply for this specific position and your skills that are specifically adapted to the chosen topic; providing support evidence to your arguments.
Contact details of 2 precious supervisors or employers who can give recommendation letters.
Please send your application to email: recruitment@mbu.cas.cz and make sure to include this identification code: Postdoc.13.2026.MBU, as it is essential for processing your application.
Application deadline: 16/11/2026 or until the position is filled
Mgr., RNDr. Dagmar Šrůtková, Ph.D.
Vědecká pracovnice
Laboratoř gnotobiologie
+420491418533
dagmar.srutkova@mbu.cas.cz